Health & Wellness Mission Viejo, CA

We empower you
to do what inspires you in life.


Welcome to Nexus HealthSpan situated in Mission Viejo, CA. Nurse Practitioner Zachary Lott specializes in personalized holistic treatment plans for heart attack prevention, stroke prevention, diabetes prevention, hormone health (including BHRT and TRT), weight loss, and nutrition counseling. We are pleased to offer the latest techniques and technologies, including CIMT ultrasound testing, a cardiovascular disease screening tool; and focused shockwave therapy, a treatment for erectile dysfunction. We are excited about getting to know and working with Orange County, CA area patients. Set up your consultation with us today.

About Us


Nexus HealthSpan offers high-quality medical care for preventing and treating chronic diseases, as well as common men's and women's health concerns. Whether you are experiencing a hormonal imbalance, erectile dysfunction, or are interested in learning how to prevent a heart attack or stroke, each of our services is personalized to fit your unique needs and lifestyle. We invite you to browse our full menu of services and schedule an appointment today.

Cardiovascular Health

Your cardiovascular health can be easily screened with CIMT testing. This noninvasive ultrasound can reveal cardiovascular disease in seconds.

Health and Wellness

Elevate your overall health and address your concerns with our health and wellness treatments, which include IV therapy and vitamin supplements.

Erectile Dysfunction Treatment

Don't let erectile dysfunction ruin your self-confidence! Contact us to learn more about focused shockwave therapy, PRP, or TriMix penile injections.

Weight Loss

We are committed to helping men and women reach and maintain a healthy weight and achieve a more balanced relationship with food.

Testosterone Replacement

Testosterone replacement therapy has a variety of benefits, such as improved libido and mood, better quality sleep, and more muscle mass.

Women’s Hormone Replacement

Bioidentical hormone replacement therapy improves energy levels, mental focus, and sexual function in women with a hormone imbalance.

All Services


Zachary Lott is a nurse practitioner who specializes in vascular health and cardiovascular disease prevention, men's sexual health, and bioidentical hormone replacement therapy in Mission Viejo, CA. He takes the time to get to know his patients in order to create patient-focused treatment plans that emphasize whole-body wellness and disease prevention.

Learn More


Visit our personalized, secure patient portal for 24-hour access to conveniently communicate with your healthcare provider, view your health records, review visit summaries, pay a bill online, and more.

Account Login

Online Scheduling


Mr Lott was so awesome to deal with and very informative on what needed to be done and for what I needed to change. He looked into my labs and knew right away a few things that nobody else has ever told me or ever looked at. I would highly recommend to schedule a visit and make a change to your life so you feel better. I am on a pathway to a better life feeling better and with more energy. Thanks Zachary Lott!!

K.K. Google

Dr Lott is great at what he does, he has been so thorough and helpful in getting me back on track with my health. He’s been able to diagnose and treat issues that my family doc blew off for years.

S.J. Google

Amazing human being. Helped my parents look and feel better! Thank you!

K.J. Google

Very thorough ! Very knowledgeable! Easy to communicate with! The best I’ve ever been to! Thanks

P.R. Google

Nexus has been a game changer!! Dr Lott has changed my life. I highly recommend him, his expertise in hormones far exceeds any doctor I’ve seen. Issues that were blown off by other doctors are completely resolved after getting things balanced correctly by Nexus HealthSpan.

S.K. Google


Total Reviews


Average Rating


26732 Crown Valley Parkway

Suite 371

Mission Viejo, CA 92691





Learn More

*Individual results are not guaranteed and may vary from person to person. Images may contain models.