Zachary Lott, MSN, ARNP, AGACNP-BC

Nurse practitioner and cardiovascular disease specialist Zachary Lott earned his Master of Science in nursing and a nurse practitioner master's certificate from California State University, Long Beach. He is board certified by the American Nurses Credentialing Center in adult-gerontology acute care. His vast experience working with critically ill patients inspired him to find a preventive treatment approach focused on patient education and a whole-health approach to medical care. At Nexus HealthSpan, Zachary's patients receive personalized treatment plans that include lifestyle management, genetic testing, and allopathic and complementary medicine. With his help, patients learn how their diet, exercise, sleep, and hormones impact their overall health and understand the appropriate steps to take in order to prevent adverse health events, like heart attacks, strokes, and diabetes.


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Zachary is a certified provider of the Bale-Doneen Method after receiving heart attack, stroke, and diabetes prevention training from Dr. Brad Bale and Dr. Amy Doneen. His training also includes advanced bioidentical hormone replacement therapy by Dr. Neal Rouzier. Zachary earned a certification from the Academy of Preventive and Innovative Medicine and is a member of the American Heart Association Council on Lifestyle and Cardiometabolic Health and the National Lipid Association.



Specialties and Expertise

Zachary's many specialties include the treatment of bioidentical hormone replacement therapy, testosterone replacement therapy, men's sexual health, and lipidology. He is also skilled in educating and treating patients about cardiovascular disease prevention.

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26732 Crown Valley Parkway Suite 371

Mission Viejo, CA 92691

Call: 949-868-0387

Zachary Lott Videos

Trusted, Proven

Nexus has been a game changer!! Dr Lott has changed my life. I highly recommend him, his expertise in hormones far exceeds any doctor I’ve seen. Issues that were blown off by other doctors are completely resolved after getting things balanced correctly by Nexus HealthSpan.

S.K. Google

Amazing human being. Helped my parents look and feel better! Thank you!

K.J. Google

Very thorough ! Very knowledgeable! Easy to communicate with! The best I’ve ever been to! Thanks

P.R. Google

Mr Lott was so awesome to deal with and very informative on what needed to be done and for what I needed to change. He looked into my labs and knew right away a few things that nobody else has ever told me or ever looked at. I would highly recommend to schedule a visit and make a change to your life so you feel better. I am on a pathway to a better life feeling better and with more energy. Thanks Zachary Lott!!

K.K. Google

Dr Lott is great at what he does, he has been so thorough and helpful in getting me back on track with my health. He’s been able to diagnose and treat issues that my family doc blew off for years.

S.J. Google


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